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Ruben Santiago, PharmD on Instagram: "2025 ends with a bang with Andexxa (coagulation factor Xa [recombinant], inactivated-zhzo) no longer being commercially sold by AstraZeneca in the US after December 22, 2025. 💉 Recall, Andexxa is a modified recombinant inactive form of human factor Xa and works by binding and sequestering factor Xa inhibitors. As a result, this reduces factor Xa activity and restores thrombin generation. 💉 Looks like 4F-PCC is what we have for now for FXaI anticoagulation
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