Jan 31, 2026 · Article Open access Published: 31 January 2026 Hemp seed extract exerts cytostatic effects through metabolic stress and autophagy modulation in malignant cells Stefania Moccia, Maria …

Introduction: The hempseed oil, suitable for human feeding, can be obtained by cold pressing of seed belonging to a non-pharmaceutical hemp variety (Cannabis sativa L.). Beyond its nutritional value …

Feb 2, 2026 · This stress led to G1 phase cell cycle arrest without triggering apoptosis. Notably, pharmacological inhibition of autophagy with chloroquine enhanced the antiproliferative effects of the …

More interestingly, Hemp oil showed a significant decrease in Bcl2 and P13k either alone or in combination with γ radiation. Finally, this study documented the possible role of hemp oil in inducing …

Autophagy induction mediated by polar hemp seed extract in target cells The absence of pronounced apoptotic cell death, coupled with the OPE-induced proliferation delay and the emergence of …

Sep 24, 2023 · The Impact of Hemp Seed Oil on Drug-Drug Interactions: A Comprehensive Review of Potential Mechanisms and Clinical Implications

Feb 7, 2026 · Hemp Seeds: Hemp seeds are a rich source of nutrients and can be eaten raw. They have lots of protein and essential fatty acids and can be used topically for a variety of health issues.

Mar 25, 2026 · Could hemp seed extract be combined with other cancer treatments? The study suggests potential for combination therapy, particularly with autophagy inhibitors like chloroquine, …

In some cases, autophagy acts as a death mechanism or as a cytoprotective mechanism, depending on the cellular context and the strength and duration of the triggering stimulus. Much more needs to be …

Jan 31, 2026 · These findings identify OPE as a metabolic modulator capable of inducing an AMPK-dependent cytostatic effect in colorectal cancer cells, supporting its potential as a non-psychotropic, …