Forbes

Creating An Effective Case Study: 12 Important Tips To Remember

The practical application of a theory or idea is the most effective way of demonstrating its usefulness. Case studies allow for the dissection of practical applications to uncover the thinking that ...
Nature

Safety and biodistribution studies of an HSV multigene vector following intracranial delivery to non-human primates

To further take advantage of multigene treatments, we engineered a multigene vector (NUREL-C2) that simultaneously expressed all four transgenes (HSV-TK, ICP0, Cx43, and TNFα) and applied this vector ...
GEN

High Dose AAV Vector Experiments Prove Extremely Toxic in Animal Studies

Gene Therapy Innovator Dr. James Wilson Raises Serious Concerns in New Report Gene therapy pioneer James M. Wilson, M.D., Ph.D., and colleagues have detailed in a new study, instances of severe, ...
Nature

Gene transfer vector biodistribution: pivotal safety studies in clinical gene therapy development

In the field of gene transfer medicine, a range of vectors that have different properties might be used. On top of the intrinsic vector features, transgene and expression cassette characteristics as ...