Array comparative genomic hybridization (CGH) is illuminating DNA copy number variations (CNV) throughout the genome to diagnose disease etiology and to help tailor treatment regimens for patients to ...
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Genetic aberrations that cause a gain or loss of chromosomal material are associated with mental retardation and congenital malformations and linked to development of cancer. Comparative genomic ...
Move over karyotypes—genetic disorder detection has vastly improved. Researchers are now using array CGH (aCGH), to quickly scan through an entire genome for imbalances.
Comparative genomic hybridization (CHG) provides the densest coverage of probes for CNV detection, but the traditional technique using bacterial artificial chromosome arrays is time consuming and not ...