Glutamate receptors mediate most rapid excitatory neurotransmission in the CNS and are important in neuronal development, synaptic plasticity, and learning and memory. Glutamate receptors are highly ...
The inhibition of N-type calcium channels by opioid receptor like receptor 1 (ORL1) is a key mechanism for controlling the transmission of nociceptive signals. We recently reported that signaling ...
Drug discovery is shifting from static snapshots to moving pictures. Instead of inferring how medicines work from end results, researchers are now watching individual molecules collide with cell ...