The spindle apparatus of Coprinus micaceus begins to develop from the diglobular polar body outside the nucleus. During both meiotic divisions it operates inside the nuclear envelope and consists of ...

The mitotic spindle, an apparatus that segregates chromosomes during cell division, may be more complex than the standard textbook picture suggests, according to researchers at the Harvard School of ...

Researchers from Ludwig-Maximilians-Universitaet (LMU) in Munich have identified a signaling pathway that restricts cleavage furrow formation to the mid-plane of the cell. Cell division is a ...

Researchers have for the first time directly observed the “molecular motor”, called Xkid, that plays a critical role in facilitating the proper alignment of chromosomes during cell division. The study ...

The spindle assembly checkpoint arrests mitotic progression until each kinetochore secures a stable attachment to the spindle. Despite fluctuating noise, this checkpoint remains robust and remarkably ...

The findings shed light on the mechanisms behind "self-organization" - an essential characteristic of biological structures. Organisms are composed of a variety of structures including muscles, ...

Architectural integrity of the mitotic spindle is required for efficient chromosome congression and accurate chromosome segregation to ensure mitotic fidelity. Tumour suppressor PTEN has multiple ...

The mitotic spindle, an apparatus that segregates chromosomes during cell division, may be more complex than the standard textbook picture suggests. The mitotic spindle, an apparatus that segregates ...