A review highlights new and emerging treatments for generalized pustular psoriasis, with a focus on IL-36 inhibitors.

Localized pustular psoriasis is a term that refers to a limited area of small pus-filled blisters on your skin, typically on your hands or feet. It is distinct from generalized pustular psoriasis (GPP ...

The US Food and Drug Administration (FDA) has approved spesolimab-sbzo, an interleukin (IL)-36 receptor antagonist, for the treatment of generalized pustular psoriasis (GPP) in adults and in pediatric ...

GPP can be triggered by the initiation and withdrawal of various medications, in particular the withdrawal of corticosteroids, and by infections, stress, and other conditions. 1,5,6,10 Patients with a ...

Please provide your email address to receive an email when new articles are posted on . Imsidolimab yielded a response rate of 75% at 16 weeks in patients with generalized pustular psoriasis. No ...

Credit: Boehringer Ingelheim. The approval was based on data from the phase 2 Effisayil-2 study which included patients 12 years of age and older and weighing at least 40kg with a history of at least ...

Please provide your email address to receive an email when new articles are posted on . The FDA expanded Spevigo’s approval to include children aged 12 years and older weighing 40 kg or more. The ...

Generalized pustular psoriasis (GPP) is a rare, severe form of pustular psoriasis that affects large areas of the body and can cause life threatening symptoms like high fever and rapid pulse. The ...

INGELHEIM, Germany--(BUSINESS WIRE)--Today, at the 25 th World Congress of Dermatology (WCD), Boehringer Ingelheim presented new late-breaking data from the EFFISAYIL™ 2 trial showing that spesolimab ...

A team from Nagoya University in Japan has identified previously unidentified gene variants that are associated with the development of generalized pustular psoriasis (GPP). The team's findings, ...

“EFFISAYIL™ 2 is the first and largest multinational randomized clinical trial to evaluate a treatment for the prevention of GPP flares,” said Bruce Strober, MD, PhD, Clinical Professor, Dermatology, ...