BACKGROUND: Despite antiplatelet therapy, some patients remain at high ischemic risk because of drug nonresponsiveness or high residual platelet reactivity). We aimed to target an orphan platelet GPCR ...

Boston, MA - A new report from the Framingham Offspring Study adds to the understanding of how alcohol can act as an anticoagulant [1]. It seems that it affects both platelet aggregation and ...

IF enhances the production of IPA from intestinal Clostridium sporogenes, which directly attenuates platelet activation and thrombosis, and alleviates microvascular thrombosis after I/R injury by ...

Platelet transfusions are essential in managing bleeding and hemostatic dysfunction, and can be expanded to be used as cell therapy for a variety of diseases. The efforts to create such cell therapies ...

Study finds that a high-fat diet boosts platelet activation and tumor cell homing—effects reversible with diet change or platelet depletion. Study: The Impact of a High -Fat Diet and Platelet ...

Here we describe a female patient who presented with pulmonary embolism and deep-vein thrombosis (DVT) in 2007 at 22 years of age and was treated for 6 months with phenprocoumon (vitamin K antagonist) ...

A simple blood test for platelet activity at middle age could one day help identify people at risk for Alzheimer's disease decades ahead of time, allowing for possible preventive therapy. According to ...