MHC Class II molecules are integral to the adaptive immune response, serving as specialised antigen-presenting proteins on the surface of professional antigen-presenting cells. They bind peptide ...

D.H. Fremont, M. Matsumura, E.A. Stura, P.A. Peterson, I.A. Wilson, "Crystal structures of two viral peptides in complex with murine MHC class I H-2Kb," Science, 257: ...

MHC class II molecules are central to the adaptive immune response, serving as the means by which antigen-presenting cells, notably dendritic cells, display processed peptides to CD4+ T cells. This ...

Controlling infectious diseases—especially zoonoses—is critical for both the economy and public health. Developing safe, effective vaccines remains the most reliable strategy for disease control, but ...

A new study sheds light on why some patients with the most aggressive form of ovarian cancer respond better to treatment than others. Tumors positive for a molecule called MHC class II are linked to ...