Human DNA constantly refolds in 3D space, and these looping dynamics regulate gene expression and cell identity.

State Key Laboratory of Gene Expression, Westlake University has the following research output in the current window (1 November 2024 - 31 October 2025) of the Nature Index. Click on Count to view a ...

A study published today in Science Advances describes new technology developed by the Rice University lab of bioengineer Jerzy Szablowski that could be a game changer for brain-based gene therapy.

Inside every cell, thousands of molecular signals collide, overlap, and compensate, obscuring the true drivers of gene ...

Scientists have identified how specific genetic changes function in cells to influence disease risk and other human health ...

Research collaboration: Genomics of Gene Expression Laboratory is a research collaboration whose article contributions are accrued to its participating partner institutions. Identify research insights ...

The Medical Genetics Multiomics Laboratory (MGML) is an academic clinical genetic testing laboratory from Baylor College of Medicine. The MGML supports the academic mission of Baylor College of ...

Rapidly testing hundreds of thousands of DNA sequences, scientists identified specific genetic variations contributing to blood pressure, cholesterol, and blood sugar.

DNA is the blueprint of life. Genes encode proteins and serve as the body's basic components. However, building a functioning ...

While widely adopted for comprehensive transcriptome profiling, the methods of poly-A selected or ribodepleted RNA-sequencing may have key limitations, including input mass requirements, inefficient ...

Scientists at the MRC Laboratory of Medical Sciences (LMS) have discovered a DNA-based “dimmer switch” that regulates the activity of a critical developmental gene, Cdx2. This work could pave the way ...