ascopubs.org

Open-Label, Phase II Trial of Extracellular Regulated Kinase Inhibition Alone and in Combination With Autophagy Inhibition in Patients With Metastatic Pancreatic Cancer

Mucin 16–Directed Therapy in Pediatric Sarcomas: Case Evidence of Ubamatamab Efficacy in Epithelioid Sarcoma and Its Implications for Other Sarcoma Subtypes Eligible patients had metastatic PDAC and ...
GEN

Role of Extracellular Phosphorylation at Synapses Informs Pain Research

Researchers headed by a team at the University of Texas at Dallas’ Center for Advanced Pain Studies (CAPS) have made a fundamental discovery about a key mechanism that enables nervous system ...
News Medical

Scientists reveal new insights into how red light-regulated histidine kinases function

Scientists have revealed new information on how red light-regulated histidine kinases function. According to the study, altering of the length of a specific 'linker helix' region of the protein can ...
Phys.org

Kinase enzymes exist throughout tree of life—those found in bacteria may be vulnerable targets for new antibiotics

Enzymes known as kinases play a critical role in cell growth, metabolism and signaling in a multitude of organisms across the tree of life—from algae to helminths to mammals. Now, scientists have ...