Recently published results from an evaluation of 1,065 chemical and drug substances using the devTOX quickPredict (devTOXqP) screening platform developed by Stemina Biomarker Discovery, Inc.

This chapter presents a historical perspective of the field of developmental toxicology and then an analysis of various mechanisms by which agents cause developmental toxicity, as currently understood ...

AMeD syndrome is a severe genetic condition found in children that present with accelerated aging, global developmental delay and bone marrow failure, among others, progressing to Myelodysplastic ...

There is a great need to reduce the cost of developing new pharmaceuticals, now approaching $900 million per drug. About 75% of this cost is attributed to failed drugs. The FDA estimates that a 10% ...

Association between physical activity, immune-related adverse events, and mortality in patients undergoing immune checkpoint inhibition. This is an ASCO Meeting Abstract from the 2023 ASCO Annual ...

As pressure increases on major pharma to bring new compounds into development, so too does pressure to make sure that these compounds are safe to test in humans. As evidenced in the TGN1214 trial last ...

Between 2% and 3% of all live-born infants are estimated to have a major developmental defect identified at birth (ICBD 1991; CDC 1995; Holmes 1997; March of Dimes 1999). The percentage increases ...