A new AI-driven framework enables highly accurate prediction of RNA splicing and isoform usage for therapeutic applications.

RNA is the means of translating the genetic code embedded in DNA into proteins, which serve as enzymes, transporters, ...

R-loops are structures that form when a strand of RNA (red) forms a stable structure with double-stranded DNA, causing one strand of the DNA to form a loop. R-loops are associated with gene ...

A new artificial intelligence model can improve the process of drug and vaccine discovery by predicting how efficiently specific mRNA sequences will produce proteins, both generally and in various ...

A wave of AI foundation models built on plant DNA sequences is giving researchers new tools to annotate genomes, predict gene function, and measure crop traits faster than traditional methods allow.

RNA molecules carry instructions from DNA for making proteins that carry out much of the work of living cells. Knowing where these molecules are located in complex tissues is a critical part of ...

New CRISPR paradigm: HKUST scientists created a DNA-guided Cas12a system that targets RNA, reversing the traditional RNA-guided DNA model. Practical advantages: The DNA guides are more stable, cheaper ...

An experimental RNA-based therapy shows promise for ALS by preventing TDP-43 protein clumping. The therapy halted motor neuron loss in mouse models. Researchers hope to one day move the treatment to ...