Type 1 diabetes is caused by an insufficient production of the hormone insulin by cells in the pancreas called beta cells and estimated to affect 9.5 million people worldwide. Low insulin levels allow ...
In type 1 diabetes, the immune system starts to destroy insulin-producing beta cells in the pancreas. Progressive loss of these cells destabilizes the body's glucose levels and drives the course of ...
Scientists at City of Hope have uncovered a gene called SMOC1 that plays a surprising role in the development of type 2 diabetes (T2D) by converting pancreatic cells that normally produce insulin into ...
Diabetes is characterized by variable loss of insulin-producing beta cells, and new regenerative approaches to increasing the functional beta cell mass of patients hold promise for reversing disease ...
Human islet microtissues (hIsMTs) (InSphero, MT-04-002-01-60) were generated after dispersion and reaggregation of primary human islets from a single donor (UNOS ID #ALIR128; male; 41 y.o.; Hispanic; ...
Researchers have discovered a novel approach to protecting insulin-producing beta cells from the damaging effects of glucolipotoxicity - a harmful condition linked to the progression of type 2 ...
GLP-1s are building a reputation as "wonder drugs." First characterized for their ability to improve insulin release and treat diabetes, the drugs were later found to promote weight loss and improve ...
Pancreatic beta cells are cells that produce insulin, the hormone responsible for regulating blood glucose levels. Diabetes develops when beta cells can no longer produce or secrete enough insulin to ...
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